
Bloating and gas are often dismissed as the price of a heavy meal, but for many, these symptoms are chronic and debilitating. When healthy bacteria migrate from the large intestine into the small intestine, they disrupt the delicate balance of your digestive system. This condition, known as Small Intestinal Bacterial Overgrowth (SIBO), requires specialized diagnostic tools and a targeted approach.
Recognizing the Common Symptoms of Small Intestinal Bacterial Overgrowth
SIBO occurs when the population of bacteria in the small intestine exceeds normal levels, leading to the fermentation of carbohydrates before they can be absorbed. This process produces excess gas, which is the primary driver of patient discomfort. Common clinical presentations include:
- Excessive Bloating: Often described as looking "six months pregnant" by the end of the day.
- Altered Bowel Habits: Patients may experience chronic diarrhea, constipation, or a fluctuating mix of both.
- Abdominal Pain: Cramping that typically intensifies after consuming fiber or sugar.
- Nutrient Malabsorption: In advanced cases, bacteria consume B12 and bile salts, leading to unintended weight loss or vitamin deficiencies.
Understanding the Underlying Causes of SIBO
The small intestine normally remains relatively sterile through a combination of stomach acid, bile, and the Migrating Motor Complex (MMC), a wave-like motion that "sweeps" debris into the colon. SIBO is rarely a primary diagnosis; it is usually a symptom of an underlying motility or structural issue. Key triggers include:
- Impaired Motility: Conditions like diabetes or hypothyroidism can slow down the MMC, allowing bacteria to stagnate and multiply.
- Structural Abnormalities: Scar tissue from previous abdominal surgeries or conditions like Crohn’s disease can create "blind loops" where bacteria thrive.
- Low Stomach Acid: Chronic use of proton pump inhibitors (PPIs) may reduce the acid barrier that normally kills ingested bacteria.
The Importance of Precise Testing for SIBO Diagnosis
Because the symptoms of SIBO overlap significantly with Irritable Bowel Syndrome (IBS) and Celiac disease, an accurate diagnosis is essential for effective treatment. The gold standard for non-invasive testing is the Hydrogen and Methane Breath Test.
During this test, you consume a sugar solution (glucose or lactulose). As the bacteria in the small intestine ferment the sugar, they release hydrogen or methane gas, which is absorbed into the bloodstream and exhaled. By measuring these gases at specific intervals, we can determine the location and severity of the overgrowth.
Personalized Treatment Strategies for Lasting SIBO Relief
Managing SIBO involves more than a simple course of antibiotics. To prevent recurrence, we must address the root cause and support the gut's natural clearing mechanism. Treatment often involves a combination of rifaximin, prokinetic agents to stimulate motility, and specific dietary protocols like the Low FODMAP diet.
If you are struggling with persistent digestive distress that hasn't responded to standard treatments, it may be time for a specialized evaluation. Our clinical team is dedicated to uncovering the root of your symptoms rather than just masking the pain. Book an appointment to discuss whether a SIBO breath test is the right next move for your digestive health.
AUTHORS:
Adeeb J. Dwairy, M.D., is a Houston-born gastroenterologist at Houston Regional Gastroenterology Institute, treating patients in Sugar Land and Humble with expertise shaped by extensive training at UT Houston.
Sushovan Guha, MD, MA, PhD, FASGE, AGAF, is a Houston-based gastroenterologist and hepatologist at Houston Regional Gastroenterology Institute with extensive academic experience, specializing in general GI care, colorectal cancer prevention, and advanced endoscopic procedures.

