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The role of weak acids with pH values in the range of 4–7 has been implicated in the symptoms of gastroesophageal reflux disease (GERD). Prostaglandin E2 (PGE2) is associated with heartburn symptom in GERD patients; however, the precise productive mechanisms remain unclear.

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Source: Nature

  • The University of Texas Health Science Center at Houston
  • Baylor College of Medicine
  • Baylor University
  • Houston Methodist, Houston
  • American College of Gastroenterology