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  • Colorectal cancers raise defensive barrier in response to chemotherapy

    Experiments with fluorouracil and irinotecan, two drugs given in combination as the first-line treatment for colorectal cancer, revealed that cancer cells respond to the treatment by secreting copious amounts of mucin.

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  • Cutting off liver cancer's nutrient supply chain

    The World Health Organization projects that starting in 2030, over a million people will die each year from liver cancer. Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer, former postdoc Wai Kit Ma, and Dillon Voss, a Stony Brook University M.D.-Ph.D. student-in-residence in Krainer's lab, have come up with a way to interfere with the energy pathway that allows this cancer to grow and spread.

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  • The Effect of Smoking on GERD and Acid Reflux

    Heartburn, or acid reflux, is that troublesome burning sensation in your chest due to rising gastric acid. When you experience this condition on a chronic basis, it’s possible that you have gastroesophageal reflux disease (GERD). If you smoke, you may be increasing the risk that you’ll develop GERD.

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  • ASTRO provides new guidance on the use of external beam radiation therapy for primary liver cancers

    A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance on the use of radiation therapy to treat adult patients with primary liver cancers using external beam radiation therapy (EBRT). Evidence-based recommendations outline indications and optimal EBRT dosing, techniques and treatment planning for patients with hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (IHC), with a strong emphasis on multidisciplinary care. The guideline, ASTRO's first for primary liver cancers, is published in Practical Radiation Oncology.

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  • AI-driven medical imaging may help fight against rectal cancer

    Building on its successes in applying artificial intelligence (AI) to medical imaging to enhance treatment of other diseases, a Case Western Reserve University-led team next will test its approach with rectal cancer patients.

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  • GERD in infants and children: What to know

    Pediatric gastroesophageal reflux disease (GERD) is a condition in which stomach acid flows into the esophagus of an infant or child, causing what is commonly known as heartburn. Without treatment, this backflow of acid can irritate and damage the esophageal lining.

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  • Trial Data May Signal Paradigm Shift In GERD, Esophageal Illnesses

    Many esophageal diseases, including gastroesophageal reflux, appear to be driven by a dysregulated esophageal microbiome, new research indicates.

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  • What are the signs of throat cancer?

    Throat cancer is cancer that develops in a person’s throat. Signs of throat cancer include vocal changes, difficulty swallowing and breathing, and a lump on the neck.

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  • What to know about common digestive issues, their causes, and symptoms

    Common digestive issues include constipation, diarrhea, bloating, and the feeling of an unfinished bowel movement. These are often symptoms of different digestive disorders, such as irritable bowel syndrome (IBS), ulcerative colitis (UC), and Crohn’s disease.

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  • Heartburn drugs may have unexpected benefits on gum disease

    New research found that patients who used drugs prescribed to treat heartburn, acid reflux and ulcers were more likely to have smaller probing depths in the gums (the gap between teeth and gums)

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